The NF1 gene revisited – from bench to bedside

The NF1 gene revisited – from bench to bedside

Neurofibromatosis type 1 (NF1) is a relatively common tumour predisposition syndrome related to germline aberrations of NF1, a tumour suppressor gene. The gene product neurofibromin is a negative regulator of the Ras cellular proliferation pathway, and also exerts tumour suppression via other mechan...

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Bibliographic Details
Main Authors: Yap, Yoon-Sim, McPherson, John R, Ong, Choon-Kiat, Rozen, Steven G, Teh, Bin-Tean, Lee, Ann SG, Callen, David F
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171599/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171599/

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