Regulatory domain of troponin moves dynamically during activation of cardiac muscle

Heart muscle is activated by Ca2+ to generate force and shortening, and the signaling pathway involves allosteric mechanisms in the thin filament. Knowledge about the structure-function relationship among proteins in the thin filament is critical in understanding the physiology and pathology of the...

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Bibliographic Details
Main Authors: Sevrieva, Ivanka, Knowles, Andrea C., Kampourakis, Thomas, Sun, Yin-Biao
Format: Online
Language:English
Published: Academic Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169182/