Fructose-1, 6-bisphosphatase opposes renal carcinoma progression

Clear cell renal cell carcinoma (ccRCC), the most frequent form of kidney cancer1, is characterized by elevated glycogen and fat deposition2. These consistent metabolic alterations are associated with normoxic stabilization of hypoxia inducible factors (HIFs)3, secondary to von hippel-lindau (VHL) m...

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Bibliographic Details
Main Authors: Li, Bo, Qiu, Bo, Lee, David S.M., Walton, Zandra E., Ochocki, Joshua D., Mathew, Lijoy K., Mancuso, Anthony, Gade, Terence P.F., Keith, Brian, Nissim, Itzhak, Simon, M. Celeste
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162811/