The Centromere: Chromatin Foundation for the Kinetochore Machinery

Since discovery of the centromere-specific histone H3 variant CENP-A, centromeres have come to be defined as chromatin structures that establish the assembly site for the complex kinetochore machinery. In most organisms, centromere activity is defined epigenetically, rather than by specific DNA sequ...

Full description

Bibliographic Details
Main Authors: Fukagawa, Tatsuo, Earnshaw, William C.
Format: Online
Language:English
Published: Cell Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160344/