In vitro centromere and kinetochore assembly on defined chromatin templates

During cell division, chromosomes are segregated to nascent daughter cells by attaching to the microtubules of the mitotic spindle through the kinetochore. Kinetochores are assembled on a specialized chromatin domain, called the centromere that is characterized by the replacement of nucleosomal hist...

Full description

Bibliographic Details
Main Authors: Guse, Annika, Carroll, Christopher W., Moree, Ben, Fuller, Colin J., Straight, Aaron F.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175311/