Substrate recognition of holocytochrome c synthase: N-terminal region and CXXCH motif of mitochondrial cytochrome c

•Holocytochrome c synthase (HCCS) does not attach heme to cytochromes lacking the histidine in the CXXCH motif.•HCCS can recognise C-terminally truncated cytochromes c.•The aromatic nature of, or possibly shape complementarity to, F15 in cytochrome c is important for recognition by HCCS.•The spacing...

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Bibliographic Details
Main Authors: Zhang, Yulin, Stevens, Julie M., Ferguson, Stuart J.
Format: Online
Language:English
Published: Elsevier Science B.V 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158909/