Lysine Acetylation Controls Local Protein Conformation by Influencing Proline Isomerization

Lysine Acetylation Controls Local Protein Conformation by Influencing Proline Isomerization

Gene transcription responds to stress and metabolic signals to optimize growth and survival. Histone H3 (H3) lysine 4 trimethylation (K4me3) facilitates state changes, but how levels are coordinated with the environment is unclear. Here, we show that isomerization of H3 at the alanine 15-proline 16...

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Bibliographic Details
Main Authors: Howe, Françoise S., Boubriak, Ivan, Sale, Matthew J., Nair, Anitha, Clynes, David, Grijzenhout, Anne, Murray, Struan C., Woloszczuk, Ronja, Mellor, Jane
Format: Online
Language:English
Published: Cell Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157579/

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