Lysine Acetylation Controls Local Protein Conformation by Influencing Proline Isomerization
Gene transcription responds to stress and metabolic signals to optimize growth and survival. Histone H3 (H3) lysine 4 trimethylation (K4me3) facilitates state changes, but how levels are coordinated with the environment is unclear. Here, we show that isomerization of H3 at the alanine 15-proline 16...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Cell Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157579/ |