The Use of a Stably Expressed FRET Biosensor for Determining the Potency of Cancer Drugs

Many cancer drugs are intended to kill cancer cells by inducing apoptosis. However, the potency assays used for measuring the bioactivity of these products are generally cell viability assays which do not distinguish between cell death and growth inhibition. Here we describe a cell-based fluorescenc...

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Bibliographic Details
Main Authors: Bozza, William P., Di, Xu, Takeda, Kazuyo, Rivera Rosado, Leslie A., Pariser, Sarah, Zhang, Baolin
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154796/