Modeling DNA methylation dynamics with approaches from phylogenetics

Motivation: Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates. Genome-wide DNA methylation assays have become increasingly common, and this has enabled characterization of DNA methylation in distinct stages across different...

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Bibliographic Details
Main Authors: Capra, John A., Kostka, Dennis
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147898/