Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells

Cell populations can be strikingly heterogeneous, composed of multiple cellular states, each exhibiting stochastic noise in its gene expression. A major challenge is to disentangle these two types of variability and to understand the dynamic processes and mechanisms that control them. Embryonic stem...

Full description

Bibliographic Details
Main Authors: Singer, Zakary S., Yong, John, Tischler, Julia, Hackett, Jamie A., Altinok, Alphan, Surani, M. Azim, Cai, Long, Elowitz, Michael B.
Format: Online
Language:English
Published: Cell Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104113/