Overexpression of cytoglobin gene inhibits hypoxic injury to SH-SY5Y neuroblastoma cells

A plasmid for cytoglobin expression, pAcGFP1-C1-cytoglobin, was transfected into SH-SY5Y cells. Cobalt chloride was used to establish a model of hypoxia. Western blotting indicated that cytoglobin was overexpressed and there was low expression of hypoxia-inducible factor-1α in SH-SY5Y cells after tr...

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Bibliographic Details
Main Authors: Yu, Xiuling, Gao, Dianwen
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146124/