Downregulation of survivin by siRNA inhibits invasion and promotes apoptosis in neuroblastoma SH-SY5Y cells

Neuroblastoma is a solid tumor that occurs mainly in children. Malignant neuroblastomas have a poor prognosis because conventional chemotherapeutic agents are not very effective. Survivin, a member of the inhibitor of the apoptosis protein family, plays a significant role in cell division, inhibitio...

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Bibliographic Details
Main Authors: Zhang, L., Liang, H., Cao, W., Xu, R., Ju, X.L.
Format: Online
Language:English
Published: Associação Brasileira de Divulgação Científica 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123833/