The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

LKB1 is a master kinase that regulates metabolism and growth through adenosine monophosphate-activated protein kinase (AMPK) and 12 other closely related kinases. Liver-specific ablation of LKB1 causes increased glucose production in hepatocytes in vitro and hyperglycaemia in fasting mice in vivo. H...

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Bibliographic Details
Main Authors: Patel, Kashyap, Foretz, Marc, Marion, Allison, Campbell, David G., Gourlay, Robert, Boudaba, Nadia, Tournier, Emilie, Titchenell, Paul, Peggie, Mark, Deak, Maria, Wan, Min, Kaestner, Klaus H., Göransson, Olga, Viollet, Benoit, Gray, Nathanael S., Birnbaum, Morris J., Sutherland, Calum, Sakamoto, Kei
Format: Online
Language:English
Published: Nature Pub. Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143937/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143937/

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