The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation

The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation

Estrogen receptor α (ERα) is initially expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression by regulating the transcription of genes linked to cell proliferation. ERα status is of clinical importance, as ERα-positive breast cancers can be successfully treate...

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Bibliographic Details
Main Authors: Zhu, J, Zhao, C, Kharman-Biz, A, Zhuang, T, Jonsson, P, Liang, N, Williams, C, Lin, C-Y, Qiao, Y, Zendehdel, K, Strömblad, S, Treuter, E, Dahlman-Wright, K
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141304/

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