Cognate interactions: Extrafollicular IL-4 drives germinal-center reactions, a new role for an old cytokine

Over the past 25 years it has become clear that B and T lymphocytes go through a range of interactions and migratory events when B cells differentiate to become high-affinity, antibody-secreting cells. This B-cell differentiation is associated with multiple sequential cognate interactions. In this i...

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Bibliographic Details
Main Author: Toellner, Kai-Michael
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140537/