ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells

ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells

Embryonic stem (ES) cells are in a dynamic equilibrium of distinct functional states, characterized by the heterogeneous expression of critical pluripotency factors and regulated by a spectrum of reversible histone modifications. Maintenance of this equilibrium is a hallmark of pluripotency. Here we...

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Bibliographic Details
Main Authors: Roper, Stephen J., Chrysanthou, Stephanie, Senner, Claire E., Sienerth, Arnold, Gnan, Stefano, Murray, Alexander, Masutani, Mitsuko, Latos, Paulina, Hemberger, Myriam
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132717/

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