Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1

In a three-stage genome-wide association study among East Asian women including 22,780 cases and 24,181 controls, we identified three novel genetic loci associated with breast cancer risk, including rs4951011 at 1q32.1 (in intron 2 of the ZC3H11A gene, P = 8.82 × 10−9), rs10474352 at 5q14.3 (near th...

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Main Authors: Cai, Qiuyin, Zhang, Ben, Sung, Hyuna, Low, Siew-Kee, Kweon, Sun-Seog, Lu, Wei, Shi, Jiajun, Long, Jirong, Wen, Wanqing, Choi, Ji-Yeob, Noh, Dong-Young, Shen, Chen-Yang, Matsuo, Keitaro, Teo, Soo-Hwang, Kim, Mi Kyung, Khoo, Ui Soon, Iwasaki, Motoki, Hartman, Mikael, Takahashi, Atsushi, Ashikawa, Kyota, Matsuda, Koichi, Shin, Min-Ho, Park, Min Ho, Zheng, Ying, Xiang, Yong-Bing, Ji, Bu-Tian, Park, Sue K., Wu, Pei-Ei, Hsiung, Chia-Ni, Ito, Hidemi, Kasuga, Yoshio, Kang, Peter, Mariapun, Shivaani, Ahn, Sei Hyun, Kang, Han Sung, Chan, Kelvin Y. K., Man, Ellen P. S., Iwata, Hiroji, Tsugane, Shoichiro, Miao, Hui, Liao, Jiemin, Nakamura, Yusuke, Kubo, Michiaki, Delahanty, Ryan J., Zhang, Yanfeng, Li, Bingshan, Li, Chun, Gao, Yu-Tang, Shu, Xiao-Ou, Kang, Daehee, Zheng, Wei
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127632/