Heterodimerization of p45–p75 Modulates p75 Signaling: Structural Basis and Mechanism of Action

Heterodimerization of p45–p75 Modulates p75 Signaling: Structural Basis and Mechanism of Action

The formation of a p45-p75 heterodimer overrides p75’s inhibition of nerve regeneration by stopping p75 homodimers from forming and creating a complex with the Nogo receptor.

Bibliographic Details
Main Authors: Vilar, Marçal, Sung, Tsung-Chang, Chen, Zhijiang, García-Carpio, Irmina, Fernandez, Eva M., Xu, Jiqing, Riek, Roland, Lee, Kuo-Fen
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122344/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122344/

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