Chopper Is Prodeath Regardless of the Effect of p75ICD on Sensitivity to Oxidative Stress
Background. The intracellular domain (ICD) of the neurotrophin receptor, p75NTR, exhibits variably pro- and antiapoptotic activity and has been implicated in neurodegenerative and neurodestructive disease. The molecular determinants of these cellular effects are not completely understood. The “Chop...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166776/ |