Kinetochore–microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E
CENP-E kinesin harbors a highly elongated coiled-coil stalk. Using in vitro and in vivo approaches, we characterize a “Bonsai” version of CENP-E with a shortened stalk. We show that the stalk positively regulates CENP-E's motor activity, which is required for maintenance of kinetochore–microtub...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116301/ |