Differential roles of microglia and monocytes in the inflamed central nervous system

Phagocytic monocyte-derived macrophages associate with the nodes of Ranvier and initiate demyelination while microglia clear debris and display a suppressed metabolic gene signature in EAE.

Bibliographic Details
Main Authors:	Yamasaki, Ryo, Lu, Haiyan, Butovsky, Oleg, Ohno, Nobuhiko, Rietsch, Anna M., Cialic, Ron, Wu, Pauline M., Doykan, Camille E., Lin, Jessica, Cotleur, Anne C., Kidd, Grahame, Zorlu, Musab M., Sun, Nathan, Hu, Weiwei, Liu, LiPing, Lee, Jar-Chi, Taylor, Sarah E., Uehlein, Lindsey, Dixon, Debra, Gu, Jinyu, Floruta, Crina M., Zhu, Min, Charo, Israel F., Weiner, Howard L., Ransohoff, Richard M.
Format:	Online
Language:	English
Published:	The Rockefeller University Press 2014
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113947/

id	pubmed-4113947
recordtype	oai_dc
spelling	pubmed-41139472015-01-28 Differential roles of microglia and monocytes in the inflamed central nervous system Yamasaki, Ryo Lu, Haiyan Butovsky, Oleg Ohno, Nobuhiko Rietsch, Anna M. Cialic, Ron Wu, Pauline M. Doykan, Camille E. Lin, Jessica Cotleur, Anne C. Kidd, Grahame Zorlu, Musab M. Sun, Nathan Hu, Weiwei Liu, LiPing Lee, Jar-Chi Taylor, Sarah E. Uehlein, Lindsey Dixon, Debra Gu, Jinyu Floruta, Crina M. Zhu, Min Charo, Israel F. Weiner, Howard L. Ransohoff, Richard M. Article Phagocytic monocyte-derived macrophages associate with the nodes of Ranvier and initiate demyelination while microglia clear debris and display a suppressed metabolic gene signature in EAE. The Rockefeller University Press 2014-07-28 /pmc/articles/PMC4113947/ /pubmed/25002752 http://dx.doi.org/10.1084/jem.20132477 Text en © 2014 Yamsaki et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Yamasaki, Ryo Lu, Haiyan Butovsky, Oleg Ohno, Nobuhiko Rietsch, Anna M. Cialic, Ron Wu, Pauline M. Doykan, Camille E. Lin, Jessica Cotleur, Anne C. Kidd, Grahame Zorlu, Musab M. Sun, Nathan Hu, Weiwei Liu, LiPing Lee, Jar-Chi Taylor, Sarah E. Uehlein, Lindsey Dixon, Debra Gu, Jinyu Floruta, Crina M. Zhu, Min Charo, Israel F. Weiner, Howard L. Ransohoff, Richard M.
spellingShingle	Yamasaki, Ryo Lu, Haiyan Butovsky, Oleg Ohno, Nobuhiko Rietsch, Anna M. Cialic, Ron Wu, Pauline M. Doykan, Camille E. Lin, Jessica Cotleur, Anne C. Kidd, Grahame Zorlu, Musab M. Sun, Nathan Hu, Weiwei Liu, LiPing Lee, Jar-Chi Taylor, Sarah E. Uehlein, Lindsey Dixon, Debra Gu, Jinyu Floruta, Crina M. Zhu, Min Charo, Israel F. Weiner, Howard L. Ransohoff, Richard M. Differential roles of microglia and monocytes in the inflamed central nervous system
author_facet	Yamasaki, Ryo Lu, Haiyan Butovsky, Oleg Ohno, Nobuhiko Rietsch, Anna M. Cialic, Ron Wu, Pauline M. Doykan, Camille E. Lin, Jessica Cotleur, Anne C. Kidd, Grahame Zorlu, Musab M. Sun, Nathan Hu, Weiwei Liu, LiPing Lee, Jar-Chi Taylor, Sarah E. Uehlein, Lindsey Dixon, Debra Gu, Jinyu Floruta, Crina M. Zhu, Min Charo, Israel F. Weiner, Howard L. Ransohoff, Richard M.
author_sort	Yamasaki, Ryo
title	Differential roles of microglia and monocytes in the inflamed central nervous system
title_short	Differential roles of microglia and monocytes in the inflamed central nervous system
title_full	Differential roles of microglia and monocytes in the inflamed central nervous system
title_fullStr	Differential roles of microglia and monocytes in the inflamed central nervous system
title_full_unstemmed	Differential roles of microglia and monocytes in the inflamed central nervous system
title_sort	differential roles of microglia and monocytes in the inflamed central nervous system
description	Phagocytic monocyte-derived macrophages associate with the nodes of Ranvier and initiate demyelination while microglia clear debris and display a suppressed metabolic gene signature in EAE.
publisher	The Rockefeller University Press
publishDate	2014
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113947/
_version_	1613118725691539456

Differential roles of microglia and monocytes in the inflamed central nervous system

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