Mechanisms for Interferon-α-Induced Depression and Neural Stem Cell Dysfunction

Mechanisms for Interferon-α-Induced Depression and Neural Stem Cell Dysfunction

New neurons generated by the neural stem cells (NSCs) in the adult hippocampus play an important role in emotional regulation and respond to the action of antidepressants. Depression is a common and serious side effect of interferon-α (IFN-α), which limits its use as an antiviral and antitumor drug....

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Bibliographic Details
Main Authors: Zheng, Lian-Shun, Hitoshi, Seiji, Kaneko, Naoko, Takao, Keizo, Miyakawa, Tsuyoshi, Tanaka, Yasuhito, Xia, Hongjing, Kalinke, Ulrich, Kudo, Koutaro, Kanba, Shigenobu, Ikenaka, Kazuhiro, Sawamoto, Kazunobu
Format: Online
Language:English
Published: Elsevier 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110771/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110771/

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