Fibrin binds to collagen and provides a bridge for αVβ3 integrin-dependent contraction of collagen gels

The functional significance of fibrin deposits typically seen in inflammatory lesions, carcinomas and in healing wounds is not fully understood. In the present study, we demonstrate that fibrinogen/fibrin specifically bound to native Col I (collagen type I) and used the Col I fibre network as a base...

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Bibliographic Details
Main Authors: Reyhani, Vahid, Seddigh, Pegah, Guss, Bengt, Gustafsson, Renata, Rask, Lars, Rubin, Kristofer
Format: Online
Language:English
Published: Portland Press Ltd. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109839/