Heparin modulates the organization of hydrated collagen gels and inhibits gel contraction by fibroblasts

We studied the effects of extracellular matrix components on fibroblast contraction of hydrated collagen gels. After 4-h incubations, heparin- containing collagen gels contracted only 10% compared with 50% contraction of control gels. Contraction was not affected by hyaluronic acid, dermatan sulfate...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1987
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114446/