Heparin modulates the organization of hydrated collagen gels and inhibits gel contraction by fibroblasts
We studied the effects of extracellular matrix components on fibroblast contraction of hydrated collagen gels. After 4-h incubations, heparin- containing collagen gels contracted only 10% compared with 50% contraction of control gels. Contraction was not affected by hyaluronic acid, dermatan sulfate...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1987
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114446/ |