Aflibercept for the Treatment of Age-Related Macular Degeneration

Aflibercept is a novel, recombinant, fusion protein that consists of portions of vascular endothelial growth factor (VEGF) receptor (R) 1 and VEGFR2 extracellular domains fused to the Fc portion of human immunoglobulin G1. It exhibits higher affinity for VEGF-A/-B and binds all the VEGF isoforms (VE...

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Bibliographic Details
Main Authors: Trichonas, George, Kaiser, Peter K.
Format: Online
Language:English
Published: Springer Healthcare 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108145/