GIV/Girdin is a central hub for pro-fibrogenic signalling networks during liver fibrosis

GIV/Girdin is a central hub for pro-fibrogenic signalling networks during liver fibrosis

Progressive liver fibrosis is characterized by the deposition of collagen by activated hepatic stellate cells (HSCs). Activation of HSCs is a multiple receptor-driven process in which profibrotic signals are enhanced, and anti-fibrotic pathways are suppressed. Here we report the discovery of a novel...

Full description

Bibliographic Details
Main Authors: Lopez-Sanchez, Inmaculada, Dunkel, Ying, Roh, Yoon-Seok, Mittal, Yash, De Minicis, Samuele, Muranyi, Andrea, Singh, Shalini, Shanmugam, Kandavel, Aroonsakool, Nakon, Murray, Fiona, Ho, Samuel B., Seki, Ekihiro, Brenner, David A., Ghosh, Pradipta
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107319/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107319/

Similar Items