NCI-60 Whole Exome Sequencing and Pharmacological CellMiner Analyses

Exome sequencing provides unprecedented insights into cancer biology and pharmacological response. Here we assess these two parameters for the NCI-60, which is among the richest genomic and pharmacological publicly available cancer cell line databases. Homozygous genetic variants that putatively aff...

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Bibliographic Details
Main Authors: Reinhold, William C., Varma, Sudhir, Sousa, Fabricio, Sunshine, Margot, Abaan, Ogan D., Davis, Sean R., Reinhold, Spencer W., Kohn, Kurt W., Morris, Joel, Meltzer, Paul S., Doroshow, James H., Pommier, Yves
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102467/