Influence of Missing Values Substitutes on Multivariate Analysis of Metabolomics Data

Missing values are known to be problematic for the analysis of gas chromatography-mass spectrometry (GC-MS) metabolomics data. Typically these values cover about 10%–20% of all data and can originate from various backgrounds, including analytical, computational, as well as biological. Currently, the...

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Bibliographic Details
Main Authors: Gromski, Piotr S., Xu, Yun, Kotze, Helen L., Correa, Elon, Ellis, David I., Armitage, Emily Grace, Turner, Michael L., Goodacre, Royston
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101515/