A Loss of Function Screen of Identified Genome-Wide Association Study Loci Reveals New Genes Controlling Hematopoiesis

The formation of mature cells by blood stem cells is very well understood at the cellular level and we know many of the key transcription factors that control fate decisions. However, many upstream signalling and downstream effector processes are only partially understood. Genome wide association st...

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Bibliographic Details
Main Authors: Bielczyk-Maczyńska, Ewa, Serbanovic-Canic, Jovana, Ferreira, Lauren, Soranzo, Nicole, Stemple, Derek L., Ouwehand, Willem H., Cvejic, Ana
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091788/