Antisense Transcription Regulates the Expression of the Enterohemorrhagic Escherichia coli Virulence Regulatory Gene ler in Response to the Intracellular Iron Concentration

Enteric pathogens, such as enterohemorrhagic E. coli (EHEC) O157:H7, encounter varying concentrations of iron during their life cycle. In the gastrointestinal tract, the amount of available free iron is limited because of absorption by host factors. EHEC and other enteric pathogens have developed so...

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Bibliographic Details
Main Authors: Tobe, Toru, Yen, Hilo, Takahashi, Hiroki, Kagayama, Yoko, Ogasawara, Naotake, Oshima, Taku
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090186/