Altered translation of GATA1 in Diamond-Blackfan anemia

Altered translation of GATA1 in Diamond-Blackfan anemia

Ribosomal protein haploinsufficiency occurs in diverse human diseases including Diamond-Blackfan anemia (DBA),1,2 congenital asplenia,3 and T-cell leukemia.4 Yet how mutations in such ubiquitously expressed proteins result in cell-type and tissue specific defects remains a mystery.5 Here, we show th...

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Bibliographic Details
Main Authors: Ludwig, Leif S., Gazda, Hanna T., Eng, Jennifer C., Eichhorn, Stephen W., Thiru, Prathapan, Ghazvinian, Roxanne, George, Tracy I., Gotlib, Jason R., Beggs, Alan H., Sieff, Colin A., Lodish, Harvey F., Lander, Eric S., Sankaran, Vijay G.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087046/

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