The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia
Ribosomal biogenesis involves the processing of pre-ribosomal RNA. A deficiency of some ribosomal proteins (RPs) impairs processing and causes Diamond Blackfan anemia (DBA), which is associated with anemia, congenital malformations and cancer. p53 mediates many features of DBA, but the mechanism of...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Company of Biologists Limited
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073278/ |