The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia

Ribosomal biogenesis involves the processing of pre-ribosomal RNA. A deficiency of some ribosomal proteins (RPs) impairs processing and causes Diamond Blackfan anemia (DBA), which is associated with anemia, congenital malformations and cancer. p53 mediates many features of DBA, but the mechanism of...

Full description

Bibliographic Details
Main Authors: Danilova, Nadia, Bibikova, Elena, Covey, Todd M., Nathanson, David, Dimitrova, Elizabeth, Konto, Yoan, Lindgren, Anne, Glader, Bertil, Radu, Caius G., Sakamoto, Kathleen M., Lin, Shuo
Format: Online
Language:English
Published: The Company of Biologists Limited 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073278/