PASTA 2.0: an improved server for protein aggregation prediction

The formation of amyloid aggregates upon protein misfolding is related to several devastating degenerative diseases. The propensities of different protein sequences to aggregate into amyloids, how they are enhanced by pathogenic mutations, the presence of aggregation hot spots stabilizing pathologic...

Full description

Bibliographic Details
Main Authors: Walsh, Ian, Seno, Flavio, Tosatto, Silvio C.E., Trovato, Antonio
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086119/