Accurate phosphoregulation of kinetochore–microtubule affinity requires unconstrained molecular interactions

Accurate regulation of kinetochore–microtubule affinity is driven by incremental phosphorylation of an NDC80 molecular “lawn,” in which NDC80–microtubule bonds reorganize dynamically in response to the number and stability of microtubule attachments.

Bibliographic Details
Main Authors: Zaytsev, Anatoly V., Sundin, Lynsie J.R., DeLuca, Keith F., Grishchuk, Ekaterina L., DeLuca, Jennifer G.
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085703/