Rac1 and Aurora A regulate MCAK to polarize microtubule growth in migrating endothelial cells

A Rac1–Aurora A–MCAK signaling pathway mediates endothelial cell polarization and directional migration by promoting regional differences in microtubule dynamics in the leading and trailing cell edges.

Bibliographic Details
Main Authors: Braun, Alexander, Dang, Kyvan, Buslig, Felinah, Baird, Michelle A., Davidson, Michael W., Waterman, Clare M., Myers, Kenneth A.
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085700/