Spatial regulation of CLASP affinity for microtubules by Rac1 and GSK3β in migrating epithelial cells

Proteins that in cells specifically bind to growing microtubule plus ends (+TIPs) are thought to play important roles in polarization of the cytoskeleton. However, most +TIPs do not show a bias of their microtubule-binding behavior toward different subcellular regions. Here, we examine the dynamics...

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Bibliographic Details
Main Authors: Wittmann, Torsten, Waterman-Storer, Clare M.
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171640/