Histone H4 Lys 20 Monomethylation of the CENP-A Nucleosome Is Essential for Kinetochore Assembly

In vertebrate cells, centromeres are specified epigenetically through the deposition of the centromere-specific histone CENP-A. Following CENP-A deposition, additional proteins are assembled on centromeric chromatin. However, it remains unknown whether additional epigenetic features of centromeric c...

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Bibliographic Details
Main Authors: Hori, Tetsuya, Shang, Wei-Hao, Toyoda, Atsushi, Misu, Sadahiko, Monma, Norikazu, Ikeo, Kazuho, Molina, Oscar, Vargiu, Giulia, Fujiyama, Asao, Kimura, Hiroshi, Earnshaw, William C., Fukagawa, Tatsuo
Format: Online
Language:English
Published: Cell Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081567/