Chromosome Engineering Allows the Efficient Isolation of Vertebrate Neocentromeres
Centromeres are specified by sequence-independent epigenetic mechanisms in most organisms. Rarely, centromere repositioning results in neocentromere formation at ectopic sites. However, the mechanisms governing how and where neocentromeres form are unknown. Here, we established a chromosome-engineer...
Main Authors: | , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Cell Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925796/ |