Chromosome Engineering Allows the Efficient Isolation of Vertebrate Neocentromeres

Centromeres are specified by sequence-independent epigenetic mechanisms in most organisms. Rarely, centromere repositioning results in neocentromere formation at ectopic sites. However, the mechanisms governing how and where neocentromeres form are unknown. Here, we established a chromosome-engineer...

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Bibliographic Details
Main Authors: Shang, Wei-Hao, Hori, Tetsuya, Martins, Nuno M.C., Toyoda, Atsushi, Misu, Sadahiko, Monma, Norikazu, Hiratani, Ichiro, Maeshima, Kazuhiro, Ikeo, Kazuho, Fujiyama, Asao, Kimura, Hiroshi, Earnshaw, William C., Fukagawa, Tatsuo
Format: Online
Language:English
Published: Cell Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925796/