NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases

NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases

Transformation by tyrosine kinase oncogenes in myeloid malignancies, including BCR-ABL in chronic myeloid leukemia, FLT3ITD in acute myeloid leukemia (AML) or JAK2V617F in myeloproliferative neoplasms (MPN), is associated with increased growth and cytoskeletal abnormalities. Using targeted approache...

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Bibliographic Details
Main Authors: Reddy, Mamatha M., Fernandes, Margret S., Salgia, Ravi, Levine, Ross L., Griffin, James D., Sattler, Martin
Format: Online
Language:English
Published: 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078661/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078661/

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