Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice

Myeloid-Derived Suppressor Cells Modulate Immune Responses Independently of NADPH Oxidase in the Ovarian Tumor Microenvironment in Mice

The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immat...

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Bibliographic Details
Main Authors: Godoy, Heidi E., Khan, A. Nazmul H., Vethanayagam, R. Robert, Grimm, Melissa J., Singel, Kelly L., Kolomeyevskaya, Nonna, Sexton, Kevin J., Parameswaran, Anupama, Abrams, Scott I., Odunsi, Kunle, Segal, Brahm H.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724928/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724928/

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