Alu and LINE-1 Hypomethylation Is Associated with HER2 Enriched Subtype of Breast Cancer

The changes in DNA methylation status in cancer cells are characterized by hypermethylation of promoter CpG islands and diffuse genomic hypomethylation. Alu and long interspersed nucleotide element-1 (LINE-1) are non-coding genomic repetitive sequences and methylation of these elements can be used a...

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Bibliographic Details
Main Authors: Park, So Yeon, Seo, An Na, Jung, Hae Yoen, Gwak, Jae Moon, Jung, Namhee, Cho, Nam-Yun, Kang, Gyeong Hoon
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074093/