Hypomethylation of Alu Elements in Post-Menopausal Women with Osteoporosis

A decrease in genomic methylation commonly occurs in aging cells; however, whether this epigenetic modification leads to age-related phenotypes has not been evaluated. Alu elements are the major interspersed repetitive DNA elements in humans that lose DNA methylation in aging individuals. Alu demeth...

Full description

Bibliographic Details
Main Authors: Jintaridth, Pornrutsami, Tungtrongchitr, Rungsunn, Preutthipan, Sangchai, Mutirangura, Apiwat
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749148/