Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia

Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia

Acute myeloid leukemia (AML) is a clinically heterogeneous disease, with 5-year disease-free survival (DFS) ranging from under 10% to over 70% for distinct groups of patients. At our institution, cytarabine, etoposide and busulfan are used in first or second remission patients treated with a 2-step...

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Main Authors: Yee, Sook Wah, Mefford, Joel A., Singh, Natasha, Percival, Mary-Elizabeth, Stecula, Adrian, Yang, Kuo, Witte, John S., Takahashi, Atsushi, Kubo, Michiaki, Matsuda, Koichi, Giacomini, Kathleen M., Andreadis, Charalambos
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068832/

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