Novel Lipid-Free Nanoformulation for Improving Oral Bioavailability of Coenzyme Q10

To improve the bioavailability of orally administered lipophilic coenzyme Q10 (CoQ10), we formulated a novel lipid-free nano-CoQ10 system stabilized by various surfactants. Nano-CoQ10s, composed of 2.5% (w/w) CoQ10, 1.67% (w/w) surfactant, and 41.67% (w/w) glycerol, were prepared by hot high-pressur...

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Bibliographic Details
Main Authors: Zhou, Huafeng, Liu, Guoqing, Zhang, Jing, Sun, Ning, Duan, Mingxing, Yan, Zemin, Xia, Qiang
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068099/