A Cell-Based High-Throughput Screen Addressing 3′UTR-Dependent Regulation of the MYCN Gene
Neuroblastoma is the most common extracranial solid tumor of infancy. Amplification of MYCN oncogene is found in approximately 20 % of all neuroblastoma patients and correlates with advanced disease stages, rapid tumor progression, and poor prognosis, making this gene an obvious therapeutic target....
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer US
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067544/ |