Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn

AT-rich interaction domain molecule 3B (ARID3B) and MYCN are expressed in a portion of neuroblastoma, and form a combination that has strong oncogenic activity in mouse embryonic fibroblasts (MEFs). Here, we show that this combination can also convert neural stem cells to neuroblastoma-like tumor. T...

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Bibliographic Details
Main Authors: Kobayashi, K, Jakt, L M, Nishikawa, S-I
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664305/