Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique

Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique

Human induced pluripotent stem cells (iPSC) can be used to understand the pathological mechanisms of human disease. These cells are a promising source for cell-replacement therapy. However, such studies require genetically defined conditions. Such genetic manipulations can be performed using the nov...

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Bibliographic Details
Main Authors: Chen, Wanjuan, Liu, Jingxin, Zhang, Longmei, Xu, Huijuan, Guo, Xiaogang, Deng, Sihao, Liu, Lipeng, Yu, Daiguan, Chen, Yonglong, Li, Zhiyuan
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066246/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066246/

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