Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts

Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts

The detoxification of ammonia occurs mainly through conversion of ammonia to urea in the liver via the urea cycle and glutamine synthesis. Congenital portosystemic shunts (CPSS) in dogs cause hyperammonemia eventually leading to hepatic encephalopathy. In this study, the gene expression of urea cycl...

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Bibliographic Details
Main Authors: van Straten, Giora, van Steenbeek, Frank G., Grinwis, Guy C. M., Favier, Robert P., Kummeling, Anne, van Gils, Ingrid H., Fieten, Hille, Groot Koerkamp, Marian J. A., Holstege, Frank C. P., Rothuizen, Jan, Spee, Bart
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063766/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063766/

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