Major HGF-mediated regenerative pathways are similarly affected in human and canine cirrhosis

by Spee, Bart, Arends, Brigitte, van den Ingh, Ted SGAM, Roskams, Tania, Rothuizen, Jan, Penning, Louis C
Published 2007

Canine models of copper toxicosis for understanding mammalian copper metabolism

by Fieten, Hille, Leegwater, Peter A. J., Watson, Adrian L., Rothuizen, Jan
Published 2011

Inherited liver shunts in dogs elucidate pathways regulating embryonic development and clinical disorders of the portal vein

by van Steenbeek, Frank G., van den Bossche, Lindsay, Leegwater, Peter A. J., Rothuizen, Jan
Published 2011

Specific down-regulation of XIAP with RNA interference enhances the sensitivity of canine tumor cell-lines to TRAIL and doxorubicin

by Spee, Bart, Jonkers, Martijn DB, Arends, Brigitte, Rutteman, Gerard R, Rothuizen, Jan, Penning, Louis C
Published 2006

Regenerative and fibrotic pathways in canine hepatic portosystemic shunt and portal vein hypoplasia, new models for clinical hepatocyte growth factor treatment

by Spee, Bart, Penning, Louis C, van den Ingh, Ted SGAM, Arends, Brigitte, IJzer, Jooske, van Sluijs, Frederik J, Rothuizen, Jan
Published 2005

Morphological characterisation of portal myofibroblasts and hepatic stellate cells in the normal dog liver

by IJzer, Jooske, Roskams, Tania, Molenbeek, Ronald F, Ultee, Ton, Penning, Louis C, Rothuizen, Jan, van den Ingh, Ted SGAM
Published 2006

Distribution of extrahepatic congenital portosystemic shunt morphology in predisposed dog breeds

by Van den Bossche, Lindsay, van Steenbeek, Frank G, Favier, Robert P, Kummeling, Anne, Leegwater, Peter AJ, Rothuizen, Jan
Published 2012

No up-regulation of the phosphatidylethanolamine N-methyltransferase pathway and choline production by sex hormones in cats

by Valtolina, Chiara, Vaandrager, Arie B., Favier, Robert P., Robben, Joris H., Tuohetahuntila, Maidina, Kummeling, Anne, Jeusette, Isabelle, Rothuizen, Jan
Published 2015

Differential expression of copper-associated and oxidative stress related proteins in a new variant of copper toxicosis in Doberman pinschers

by Spee, Bart, Mandigers, Paul JJ, Arends, Brigitte, Bode, Peter, van den Ingh, Ted SGAM, Hoffmann, Gaby, Rothuizen, Jan, Penning, Louis C
Published 2005

The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns

by Boomkens, Sacha Y, Spee, Bart, IJzer, Jooske, Kisjes, Ronald, Egberink, Herman F, van den Ingh, Ted SGAM, Rothuizen, Jan, Penning, Louis C
Published 2004

COMMD1-Deficient Dogs Accumulate Copper in Hepatocytes and Provide a Good Model for Chronic Hepatitis and Fibrosis

by Favier, Robert P., Spee, Bart, Schotanus, Baukje A., van den Ingh, Ted S. G. A. M., Fieten, Hille, Brinkhof, Bas, Viebahn, Cornelia S., Penning, Louis C., Rothuizen, Jan
Published 2012

Enhanced Wnt/β-catenin and Notch signalling in the activated canine hepatic progenitor cell niche

by Schotanus, Baukje A, Kruitwagen, Hedwig S, van den Ingh, Ted SGAM, van Wolferen, Monique E, Rothuizen, Jan, Penning, Louis C, Spee, Bart
Published 2014

Altered Subcellular Localization of Heat Shock Protein 90 Is Associated with Impaired Expression of the Aryl Hydrocarbon Receptor Pathway in Dogs

by van Steenbeek, Frank G., Spee, Bart, Penning, Louis C., Kummeling, Anne, van Gils, Ingrid H. M., Grinwis, Guy C. M., Van Leenen, Dik, Holstege, Frank C. P., Vos-Loohuis, Manon, Rothuizen, Jan, Leegwater, Peter A. J.
Published 2013

Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts

by van Straten, Giora, van Steenbeek, Frank G., Grinwis, Guy C. M., Favier, Robert P., Kummeling, Anne, van Gils, Ingrid H., Fieten, Hille, Groot Koerkamp, Marian J. A., Holstege, Frank C. P., Rothuizen, Jan, Spee, Bart
Published 2014

Aberrant Gene Expression in Dogs with Portosystemic Shunts

by van Steenbeek, Frank G., Van den Bossche, Lindsay, Grinwis, Guy C. M., Kummeling, Anne, van Gils, Ingrid H. M., Koerkamp, Marian J. A. Groot., van Leenen, Dik, Holstege, Frank C. P., Penning, Louis C., Rothuizen, Jan, Leegwater, Peter A. J., Spee, Bart
Published 2013

Correction: Aberrant Gene Expression in Dogs with Portosystemic Shunts

by van Steenbeek, Frank G., Van den Bossche, Lindsay, Grinwis, Guy C. M., Kummeling, Anne, van Gils, Ingrid H. M., Koerkamp, Marian J. A. Groot., van Leenen, Dik, Holstege, Frank C. P., Penning, Louis C., Rothuizen, Jan, Leegwater, Peter A. J., Spee, Bart
Published 2013

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

by Nantasanti, Sathidpak, Spee, Bart, Kruitwagen, Hedwig S., Chen, Chen, Geijsen, Niels, Oosterhoff, Loes A., van Wolferen, Monique E., Pelaez, Nicolas, Fieten, Hille, Wubbolts, Richard W., Grinwis, Guy C., Chan, Jefferson, Huch, Meritxell, Vries, Robert R.G., Clevers, Hans, de Bruin, Alain, Rothuizen, Jan, Penning, Louis C., Schotanus, Baukje A.
Published 2015

The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders

by Fieten, Hille, Gill, Yadvinder, Martin, Alan J., Concilli, Mafalda, Dirksen, Karen, van Steenbeek, Frank G., Spee, Bart, van den Ingh, Ted S. G. A. M., Martens, Ellen C. C. P., Festa, Paola, Chesi, Giancarlo, van de Sluis, Bart, Houwen, Roderick H. J. H., Watson, Adrian L., Aulchenko, Yurii S., Hodgkinson, Victoria L., Zhu, Sha, Petris, Michael J., Polishchuk, Roman S., Leegwater, Peter A. J., Rothuizen, Jan
Published 2016